Skip to main content
. Author manuscript; available in PMC: 2019 Nov 22.
Published in final edited form as: ACS Catal. 2018 Jun 4;8(7):5947–5951. doi: 10.1021/acscatal.8b01341

Table 3.

Scope of β-aryl, β-fluoro Michael acceptors

graphic file with name nihms-1020218-t0006.jpg
a

Standard reaction conditions: 0.5 mmol 16-30a, 3.0 equiv Et3N· 3HF, 1.0 equiv p-CI BA, 5 mol % RuPhosAuCl, 5 mol % AgBF4, 4:1 MeCN:CH2CI2 [0.7M], rt, 24 h.

b

16-30b isolated as a single isomer.

c

Determined by 19F NMR spectroscopy with PhF as an internal standard.

d

1.43 M, 45 °C.

e

45 °C.

f

4.5 mmol.

g

1.25 M, 55 °C, 4.0 equiv Et3N·3HF.

h

45 °C, 48 h, 4.0 equiv Et3N·3HF.