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. 2019 Nov 22;14(11):e0225511. doi: 10.1371/journal.pone.0225511

Fig 1. Relative mRNA levels of Hedgehog signaling-related molecules in various skin tumors.

Fig 1

Expression of GLI1 (A), GLI2 (B), PTCH1 (C), PTCH2 (D), SHH (E), and SMO (F) in normal skin tissue (n = 5), basal cell carcinoma (BCC; n = 18), trichoepithelioma (TE; n = 7), pilomatricoma (PMC; n = 8), eccrine poroma (EP; n = 9), hidradenoma (HAD; n = 10), spiradenoma (SPA; n = 8), squamous cell carcinoma (SCC; n = 9), sebaceous carcinoma (SBC; n = 7), and malignant melanoma (MN; n = 8). (G) Relative expression of Hedgehog signaling molecules in BCCs (n= 18). Bars represent mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001; ns, not significant.