Fig 10. Mitochondrial DNA are released in BALF of patients with ARDS.
Mitochondrial DNA (cytochrome C oxidase III) measured by quantitative PCR in bronchoalveolar lavage fluid of patients with ARDS at day 1 and day 7 of presentation and healthy volunteers. Patients with ARDS were categorized as “highly inflammatory” (high PMN) if they contained > 80% neutrophils and > 2 mg/mL proteins or “low inflammatory” (low PMN) if they did not meet those criteria. Data are expressed as fold change over healthy volunteers and represent median with interquartile range of at least three independent experiments. *P < 0.05, Kruskall-Wallis test with FDR correction (A-B). CTL: controls (healthy volunteers), PMN: polymorphonuclear, ARDS: acute respiratory distress syndrome.