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. 2019 Nov 13;11(21):9932–9946. doi: 10.18632/aging.102417

Figure 2.

Figure 2

ping-pong mechanism. primary piRNAs bind to AGO3 or AUB proteins to form piRNA/Ago3 or piRNA/AUB complexes, generate new piRNAs using piRNA and piRNA/Ago3 or piRNA/AUB complexes as templates, using new generated piRNA to synthesis another piRNA in same method.