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. 2019 Nov 9;11(21):9738–9766. doi: 10.18632/aging.102422

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Copyright © 2019 Zhong et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Data were presented as the mean ± SD. * p<0.05, *** p<0.01. (A) The results of cell proliferation in 5 glioblastoma cell lines and HL-7702 treated with different doses of ENMD-2076 (0, 0.5, 1, 2, 4, 8μM) for 24, 48, 72 hours. (B–C) Colony formation assay results of ENMD-2076 anti-proliferative effects in C6, LN18 and T98G cells for 2 weeks. (D–E) ENMD-2076 suppressing the migration of LN18, T98G cells in the scratch assay. The wound-healing images represented the migration capacity of glioblastoma cells.