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. 2019 Nov 22;9:17370. doi: 10.1038/s41598-019-53960-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Visualization of DNA attachment through AFM. (a) AFM image of a ZnO NW decorated with Au NPs showing attachment of duplex DNA at specific sites. Height profiles of the nanowire (b) and duplex DNA strands (c) on the SiO₂ substrate. (d) AFM 3D image of (a); here the color is adjusted to see the surface of the ZnO NW. The area enclosed by the white dotted line is enlarged in (e) while the inset in (e) is the 2D AFM image with adjusted color scale. Au NPs attached to the ZnO NW surface are highlighted using red dotted lines in (e).