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. 2019 Nov 22;9:17391. doi: 10.1038/s41598-019-53642-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Vaccination with ApoB100 peptides does enhance CD8 T cell levels but not reactivity towards ApoB100 peptides in the aortic root (A) Quantification of CD8 T cell percentage in aortic cultures. (B) Representative flow cytometry plots of aortic CD8 T cell activation and (C) quantification of IFN-γ and TNF-α double positive cell % from CD8 T cells after restimulation with a mix of all peptides. Statistical analysis was performed with 1-way ANOVA and Tukey’s multiple comparisons test. Depicted as mean with SEM, *P < 0.05.