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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Melanoma Res. 2020 Feb;30(1):52ā€“61. doi: 10.1097/CMR.0000000000000625

Table 3.

Sharing of MT and WT TRB sequences with tumor in Sanger sequence data set.

n111 n110* n101* n100 n011 n010 n001
0 7 2 544 2 359 792

Sanger sequence data from 8 patients were collapsed into 3 sets: tumor, MT, or WT. Clonotypes had identical TRBV, CDR3, and TRBJ. The number of sequences shared between sets is represented by ā€˜nā€™, and the subscripts represent tumor, MT, and WT, respectively.

MT mutant; WT; wild-type; TRB, T cell receptor beta; TRBV, TRB V-region; CDR3, complementarity determining region 3; TRBJ, TRB J-region.

*

p=10āˆ’7, Monte Carlo computations, MT TRB shared with tumor compared to WT TRB shared with tumor