Figure 2. CNDP2 overexpression depletes Thr-Thr in vivo.
(A) Extracted ion chromatogram of an unknown metabolite at m/z = 219.099 from transduced livers in CNDP2-transduced (red) versus all other viral transduction groups (blue). (B-D) Structural assignment, co-elution, and tandem MS fragmentation of the endogenous m/z = 219.099 and an authentic Thr-Thr standard. For (A) and (C), chromatograms were extracted at the exact mass ± 20 ppm.
