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. 2019 Oct 14;22(2):203–211. doi: 10.22074/cellj.2020.6699

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The Cell Journal (Yakhteh) is an open access journal which means the articles are freely available online for any individual author to download and use the providing address. The journal is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported License which allows the author(s) to hold the copyright without restrictions that is permitting unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

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Fig 2 — Bisulfite DNA sequencing of the CpGs in the CDKN2A promoter. A. Diagrammatic illustration of the CDKN2A promoter-associated CpG islands, which cover the region from -161 to +181 (the translation initiation site ATG as +1). The region analyzed by bisulfite sequencing polymerase chain reaction (PCR) is depicted. This region covers 342 bp and consists of 18 CpG, B. Methylation patterns of the CDKN2A CpG island in six control and six OGD samples (each line represents an independent sample). Methylated and unmethylated CpG sites are represented as solid and open circles, respectively, and C. Statistical analysis of methylation in the two groups. Data are presented as mean ± SD. **; P<0.01, compared with the controls.