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. 2019 Oct 14;22(2):203–211. doi: 10.22074/cellj.2020.6699

Fig 3.

Fig 3

The CpG island in the CDKN2B promoter showed by bisulfite sequencing. A. Illustrative sketch of the CDKN2B promoter, which covers the region from -109 to +285. The region analyzed by bisulfite sequencing polymerase chain reaction (PCR) is depicted. This region covers 394 bp and includs 39 CpG dinucleotides, B. Methylation patterns of the CDKN2B CpG island in six control and six OGD samples. Each circle represents a single CpGs (closed and open circles show methylated and unmethylated regions, respectively), and C. Statistical analysis of methylation in the two groups. Data are presented as mean ± SD, P=0.064.