Table 2.
Distribution of the genotypes and allele frequency of rs1042522 polymorphism in breast cancer cases and controls
| Genetic analysis model | Number of case (%) | Number of control (%) | P value | OR (95% CI) |
|---|---|---|---|---|
| Genotypes | ||||
| GG | 187 (60.7) | 189 (60.2) | Reference | |
| GC | 94 (30.5) | 101 (32.2) | 0.73 | 0.94 (0.67-1.33) |
| CC | 27 (8.8) | 24 (7.6) | 0.67 | 1.38 (0.63-2.04) |
| Dominant | ||||
| GG+GC | 281 (91.2) | 290 (92.4) | Reference | |
| CC | 27 (8.8) | 24 (7.6) | 0.61 | 0.86 (0.48-1.53) |
| Recessive | ||||
| GG | 187 (60.7) | 189 (60.2) | Reference | |
| GC+CC | 121 (39.3) | 125 (39.8) | 0.89 | 0.98 (0.71-1.35) |
| Allele | ||||
| G | 468 (76.0) | 479 (76.3) | Reference | |
| C | 148 (24.0) | 149 (23.7) | 0.90 | 1.02 (0.78-1.32) |
OR; Odd ratio and CI; Confidence interval.