Table 4.
Analysis of the association between TP53 codon 72 polymorphism and breast cancer risk in different genetic models, the test of heterogeneity and publication bias
| Model | Test of association | Test of heterogeneity | Publication bias | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | Model | P value | I2 | P value (Egger’s test) | |
| Allele contrast (G vs. C) | 1.18 (0.96-1.47) | 0.13 | Random | <0.001 | 0.80 | 0.63 |
| Recessive model (GG vs. GC+CC) | 1.34 (0.95-1.89) | 0.10 | Random | <0.001 | 0.83 | 0.73 |
| Dominant model (GG+GC vs. CC) | 1.15 (0.84-1.56) | 0.38 | Random | <0.01 | 0.58 | 0.51 |
| Over dominant (GC vs. GG + CC) | 0.79 (0.58-1.06) | 0.12 | Random | <0.001 | 0.79 | 0.50 |
| Pairwise 1 (GG vs. CC) | 1.38 (0.93-2.04) | 0.11 | Random | <0.001 | 0.67 | 0.83 |
| Pairwise 2 (GG vs. GC) | 1.36 (0.95-1.95) | 0.10 | Random | <0.001 | 0.82 | 0.66 |
| Pairwise 3 (GC vs. CC) | 1.00 (0.72-1.36) | 0.97 | Random | <0.01 | 0.55 | 0.63 |
OR; Odd ratio and CI; Confidence interval.