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. 2019 Oct 14;22(2):185–192. doi: 10.22074/cellj.2020.6458

Table 4.

Analysis of the association between TP53 codon 72 polymorphism and breast cancer risk in different genetic models, the test of heterogeneity and publication bias


Model Test of association Test of heterogeneity Publication bias
OR (95% CI) P value Model P value I2 P value (Egger’s test)

Allele contrast (G vs. C) 1.18 (0.96-1.47) 0.13 Random <0.001 0.80 0.63
Recessive model (GG vs. GC+CC) 1.34 (0.95-1.89) 0.10 Random <0.001 0.83 0.73
Dominant model (GG+GC vs. CC) 1.15 (0.84-1.56) 0.38 Random <0.01 0.58 0.51
Over dominant (GC vs. GG + CC) 0.79 (0.58-1.06) 0.12 Random <0.001 0.79 0.50
Pairwise 1 (GG vs. CC) 1.38 (0.93-2.04) 0.11 Random <0.001 0.67 0.83
Pairwise 2 (GG vs. GC) 1.36 (0.95-1.95) 0.10 Random <0.001 0.82 0.66
Pairwise 3 (GC vs. CC) 1.00 (0.72-1.36) 0.97 Random <0.01 0.55 0.63

OR; Odd ratio and CI; Confidence interval.