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. 2019 Nov 8;21(11):e13371. doi: 10.2196/13371

Table 3.

Preferred terms retrieved from FAERS reports for Z-drugs.

# Eszopiclone (n=458) Zaleplon (n=77) Zolpidem (n=3448)
Preferred term n (%) Preferred term n (%) Preferred term n (%)
1 Drug ineffective 78 (17.0) Drug ineffective 18 (23) Drug ineffective 499 (14.5)
2 Insomnia 33 (7.2) Drug effect incomplete 3 (4) Insomnia 146 (4.2)
3 Product substitution issue 30 (6.6) Insomnia 3 (4) Product substitution issue 96 (2.8)
4 Dysgeusia 22 (4.8) Product quality issue 3 (4) Somnambulism 75 (2.2)
5 Product quality issue 16 (3.5) Product substitution issue 3 (4) Somnolence 59 (1.7)
6 Drug effect decreased 14 (3.1) Abnormal behavior 2 (3) Drug dependence 57 (1.7)
7 Delirium 12 (2.6) Drug hypersensitivity 2 (3) Amnesia 51 (1.5)
8 Headache 7 (1.5) Malaise 2 (3) Road traffic accident 48 (1.4)
9 Nausea 7 (1.5) Nausea 2 (3) Toxicity to various agents 47 (1.4)
10 Sleep disorder 7 (1.5) Nightmare 2 (3) Overdose 46 (1.3)