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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Leukemia. 2019 May 24;33(12):2805–2816. doi: 10.1038/s41375-019-0491-z

Figure 3. ONC212 treatment inhibits the clonogenic growth of human AML blasts but not normal hematopoietic cells.

Figure 3.

For treatment with or without ONC212 (100 or 200 nM), (A) the percentage of blast colony formation from three patient samples were examined. **; p < 0.01, ***; p < 0.005. (B) The number of blast colonies from AML patients without ONC212 treatment. (C) Hematopoietic colony formation from two healthy donor BM samples following the above-mentioned treatment. (D) Mean of each type of hematopoietic colony generated in percentage. ONC212 did not affect the frequency of each colonies. Data are shown as the mean ± SD (n = 3). N.S. = not significant.