Table 2.
Conventional 2D and TDI echocardiographic measurements by treatment group
Echocardiographic parameter | Treatment Group | Pre-Treatment (± SD) | Post-Treatment (± SD) | P-value |
---|---|---|---|---|
LVIDd indexed cm/m2 | Clofarabine | 2.28 (±0.28) | 2.26 (±0.23) | 0.74 |
LVEF (Simpson’s biplane) | Clofarabine | 0.64 (±0.06) | 0.58 (±0.08) | 0.19 |
Mitral E wave velocity cm/s | Clofarabine | 82.52 (±19.12) | 80.50 (±23.19) | 0.74 |
Mitral A wave velocity cm/s | Clofarabine | 79.29 (±16.52) | 85.83 (±21.37) | 0.07 |
E/A | Clofarabine | 1.06 (±0.25) | 0.95 (±0.20) | 0.55 |
Deceleration time ms | Clofarabine | 243 (±153.8) | 230 (±45.2) | 0.55 |
Mitral Septal s’ wave velocity cm/s | Clofarabine | 8.66 (±1.32) | 9.6 (±3.37) | 0.64 |
Mitral Septal e’ wave velocity cm/s | Clofarabine | 9.01 (±2.44) | 7.8 (±2.93) | 0.58 |
Mitral Septal a’ wave velocity cm/s | Clofarabine | 11.05 (±1.50) | 12.12 (±4.19) | 0.44 |
Mitral Lateral s’ wave velocity cm/s | Clofarabine | 9.17 (±1.88) | 9.17 (±2.49) | 0.44 |
Mitral Lateral e’ wave velocity cm/s | Clofarabine | 10.93 (±2.04) | 9.46 (±2.49) | 0.41 |
Mitral Lateral a’ wave velocity cm/s | Clofarabine | 12.36 (±2.36) | 11.38 (±1.91) | 0.33 |
RV basal diameter | Clofarabine | 2.97 (±0.47) | 2.94 (±0.69) | 0.55 |
TAPSE | Clofarabine | 2.23 (±0.45) | 2.14 (±0.21) | 0.54 |