HEMOGLOBIN-BASED OXYGEN CARRIERS: CURRENT STATE-OF-THE-ART AND NOVEL MOLECULES

. Author manuscript; available in PMC: 2019 Nov 24.

Published in final edited form as: Shock. 2019 Oct;52(1):70–83. doi: 10.1097/SHK.0000000000001009

Fig. 2. Representative approaches and design schematics for HBOCs based on chemical modification (cross-linking, surface modification, polymerization, etc.) of Hb that have undergone significant preclinical and clinical evaluation.