Table 1.
Characteristics of study patients with SCCOP (N = 564)
| Characteristics | All patients (N, %) | HPV(+) SCCOP (N, %) | HPV(−) SCCOP (N, %) |
|---|---|---|---|
| Age | |||
| ≤ 57 years | 343(60.8) | 293 (60.8) | 50 (61.0) |
| > 57 years | 221(39.2) | 189 (39.2) | 32 (39.0) |
| Sex | |||
| Male | 491(87.1) | 428 (88.8) | 63 (76.8) |
| Female | 73(12.9) | 54 (11.2) | 19 (23.2) |
| Ethnicity | |||
| Non-Hispanic white | 518(91.8) | 447 (92.7) | 71 (86.6) |
| Other | 46(8.2) | 35 (7.3) | 11 (13.4) |
| Smoking | |||
| Never | 280(49.7) | 244 (50.6) | 36 (43.9) |
| Ever | 284(50.3) | 238 (49.4) | 46 (56.1) |
| Alcohol use | |||
| Never | 187(33.2) | 158 (32.8) | 29 (35.4) |
| Ever | 377(66.8) | 324 (67.2) | 53 (64.6) |
| Index cancer stage | |||
| I or II | 36(6.4) | 33 (6.9) | 3 (3.7) |
| III or IV | 528(93.6) | 449 (93.1) | 79 (96.3) |
| Comorbidity | |||
| None or mild | 511(90.6) | 438 (90.9) | 73 (89.0) |
| Moderate to severe | 53(9.4) | 44 (9.1) | 9 (11.0) |
| Treatment | |||
| Radiotherapy only | 133(23.6) | 117 (24.3) | 16 (19.5) |
| Radiochemotherapy | 431(76.4) | 365 (75.7) | 66 (80.5) |
| Death, all causes | |||
| Yes | 78(14.0) | 66 (13.7) | 12 (14.8) |
| No | 485(86.0) | 416 (86.3) | 69 (85.2) |
| Death, owing to disease | |||
| Yes | 44(8.0) | 37 (7.7) | 7 (8.6) |
| No | 519(92.0) | 445 (92.3) | 74 (91.4) |
| Recurrence | |||
| Yes | 64(11.4) | 55 (11.4) | 9 (11.0) |
| No | 500(88.6) | 427 (88.6) | 73 (89.0) |
| Follow up (Months) | |||
| Median | 34.5 | 35.2 | 31.2 |
| Range | 0.1–207.0 | 1.3–207.0 | 0.1–77.2 |