Table 2.
Demographic characteristics, sleep profiles, and blood measurements of the OSA subgroups and the control group.
| Control (n = 21) | Mild (n = 7) | Moderate (n = 10) | Severe (n = 19) | |
|---|---|---|---|---|
| Age (years) | 39.33 ± 9.40 | 34.85 ± 8.09 | 39.40 ± 7.86 | 39.94 ± 9.40 |
| Waist-to-hip ratio | 0.87 ± 0.07 | 0.88 ± 0.05 | 0.93 ± 0.06∗ | 0.93 ± 0.09∗ |
| BMI (kg/m2) | 26.60 ± 5.31 | 29.62 ± 6.82 | 27.45 ± 2.52 | 28.21 ± 4.72 |
| AHI (events/h) | 2.47 ± 1.18 | 11.10 ± 2.66∗ | 22.29 ± 5.07∗ | 51.20 ± 13.66∗ |
| ODI (events/h) | 1.73 ± 0.98 | 9.32 ± 2.37∗ | 19.76 ± 5.46∗ | 45.42 ± 13.48∗ |
| AI (events/h) | 13.24 ± 7.65 | 16.88 ± 9.72 | 22.09 ± 4.17∗ | 52.08 ± 14.33∗ |
| Lowest SPO2 (%) | 90.70 ± 1.09 | 87.29 ± 3.30∗ | 83.60 ± 4.25∗ | 74.63 ± 8.40∗ |
| Mean SPO2 (%) | 93.53 ± 1.05 | 92.24 ± 2.01 | 91.67 ± 1.92∗ | 88.79 ± 2.91∗ |
| Duration of SPO2 < 90% (%) | 0.50 ± 1.57 | 19.77 ± 9.59∗ | 14.46 ± 6.15∗ | 22.73 ± 8.64∗ |
| TST (min) | 317.48 ± 42.53 | 311.43 ± 21.64 | 341.00 ± 46.05 | 328.11 ± 40.97 |
| REM sleep (%) | 13.52 ± 3.23 | 12.33 ± 3.58 | 10.30 ± 2.76∗ | 11.28 ± 3.39∗ |
| NREM sleep (%) | 86.48 ± 3.32 | 87.67 ± 3.58 | 89.70 ± 2.77∗ | 88.72 ± 3.39∗ |
| Sestrin2 (ng/mL) | 2.06 ± 1.76 | 2.63 ± 1.66 | 3.09 ± 1.77∗ | 5.28 ± 2.36∗ |
| TG (mmol/L) | 1.48 ± 0.46 | 2.09 ± 1.02 | 1.62 ± 0.78 | 1.83 ± 1.39 |
| TC (mmol/L) | 4.19 ± 0.83 | 4.80 ± 0.38∗ | 4.09 ± 0.52 | 4.26 ± 0.74 |
| LDL (mmol/L) | 2.30 ± 0.65 | 2.85 ± 0.42∗ | 2.31 ± 0.47 | 2.40 ± 0.64 |
| HDL (mmol/L) | 1.17 ± 0.34 | 1.00 ± 0.25 | 1.00 ± 0.20 | 1.01 ± 0.29 |
| FBG (mmol/L) | 4.36 ± 0.56 | 4.54 ± 0.75 | 4.51 ± 0.40 | 4.60 ± 0.62 |
| ESS (scores) | 6.76 ± 3.19 | 10.86 ± 2.91∗ | 10.80 ± 4.5∗ | 13.26 ± 4.51∗ |
Values are indicated as mean ± standard deviation. OSA, obstructive sleep apnea; BMI, body mass index; AHI, apnea/hypopnea index; ODI, oxygen desaturation index; AI, arousal index; SPO2, pulse oxygen saturation; TST, total sleep time; REM, rapid eye movement; NREM, nonrapid eye movement; TG, triglycerides; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; FBG, fasting blood glucose; ESS, Epworth Sleepiness Score. ∗P < 0.05 vs. the control.