Table 3.
Univariate and multivariate analysis for the safety endpoint (the composite of all-cause death or myocardial infarction) at 1 year.
| Univariate Cox proportional hazard model | Multivariate Cox proportional hazard model | |||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| ACS versus SCAD | 2.033 (1.357–3.046) | 0.001 | 1.260 (0.774–2.053) | 0.352 |
| Age ≥80 years | 2.369 (1.536–3.656) | <0.001 | 2.145 (1.358–3.386) | 0.001 |
| Male | 0.732 (0.475–1.130) | 0.159 | ||
| Current smoker | 1.260 (0.782–2.032) | 0.342 | ||
| Hypertension | 1.201 (0.745–1.937) | 0.451 | ||
| Dyslipidemia | 0.459 (0.298–0.708) | <0.001 | 0.993 (0.486–2.029) | 0.985 |
| Diabetes mellitus | 1.291 (0.861–1.935) | 0.216 | ||
| Chronic kidney disease without hemodialysis | 1.484 (0.921–2.393) | 0.105 | ||
| Chronic kidney disease with hemodialysis | 4.658 (2.927–7.499) | <0.001 | 3.895 (2.124–7.143) | <0.001 |
| Left ventricular ejection fraction <35% | 8.352 (5.366–13.002) | <0.001 | 3.223 (1.913–5.431) | <0.001 |
| Peripheral artery disease | 2.009 (1.118–3.396) | 0.009 | 1.261 (0.692–2.299) | 0.449 |
| History of stroke | 1.608 (0.911–2.837) | 0.101 | ||
| History of myocardial infarction | 0.923 (0.590–1.442) | 0.724 | ||
| Previous percutaneous coronary intervention | 0.825 (0.535–1.273) | 0.384 | ||
| Previous coronary artery bypass grafting | 1.403 (0.680–2.895) | 0.360 | ||
| Triple vessel disease | 2.470 (1.527–3.881) | <0.001 | 1.380 (0.844–2.255) | 0.199 |
| Cardiogenic shock status at procedure | 28.050 (16.864–46.656) | <0.001 | 14.228 (6.511–31.090) | <0.001 |
| Left anterior descending coronary artery | 0.835 (0.552–1.263) | 0.392 | ||
| Left circumflex coronary artery | 0.584 (0.311–1.095) | 0.094 | ||
| Right coronary artery | 1.345 (0.889–2.034) | 0.161 | ||
| Left main coronary artery | 2.066 (1.039–4.108) | 0.038 | 1.360 (0.560–1.807) | 0.360 |
| Type B2/C lesion | 1.677 (0.933–3.011) | 0.084 | ||
| Restenotic lesion | 0.546 (0.239–1.247) | 0.151 | ||
| Chronic total occlusion | 1.119 (0.542–2.309) | 0.761 | ||
| Ostial lesion | 2.921 (1.893–4.506) | <0.001 | 2.605 (1.600–4.239) | <0.001 |
| Bifurcation | 1.349 (0.867–2.099) | 0.185 | ||
| Severe calcification on angiography | 2.725 (1.808–4.107) | <0.001 | 1.364 (0.845–2.203) | 0.204 |
| Use of 2.5 mm diameter stent | 1.378 (0.914–2.077) | 0.126 | ||
| Total stent length ≥28 mm | 1.479 (0.976–2.242) | 0.065 | ||
| Use of imaging device for stent placement | 0.281 (0.164–0.481) | <0.001 | 0.765 (0.378–1.547) | 0.456 |
| Use of anticoagulant agent | 0.937 (0.499–1.757) | 0.838 | ||
| Use of statin | 0.429 (0.283–0.652) | <0.001 | 0.853 (0.419–1.737) | 0.662 |
| Use of beta-blocker | 0.752 (0.499–1.133) | 0.173 | ||
| Use of angiotensin-converting enzyme inhibitor | 0.625 (0.408–0.957) | 0.031 | 0.684 (0.436–1.073) | 0.098 |
| Use of angiotensin receptor blocker | 1.176 (0.687–2.014) | 0.554 | ||
Note. ACS: acute coronary syndrome; SCAD: stable coronary artery disease; HR: hazard ratio; CI: confidence interval.