Table 4.
Univariate and multivariate analysis for the safety endpoint (the composite of all-cause death or myocardial infarction) from 1 to 5 years.
| Univariate Cox proportional hazard model | Multivariate Cox proportional hazard model | |||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| ACS versus SCAD | 1.058 (0.789–1.418) | 0.706 | ||
| Age ≥80 years | 2.192 (1.606–2.992) | <0.001 | 2.079 (1.511–2.860) | <0.001 |
| Male | 1.099 (0.793–1.522) | 0.571 | ||
| Current smoker | 0.735 (0.501–1.077) | 0.114 | ||
| Hypertension | 1.283 (0.922–1.786) | 0.140 | ||
| Dyslipidemia | 0.615 (0.447–0.846) | 0.003 | 0.749 (0.456–1.231) | 0.254 |
| Diabetes mellitus | 1.189 (0.903–1.564) | 0.217 | ||
| Chronic kidney disease without hemodialysis | 1.931 (1.412–2.641) | <0.001 | 1.747 (1.244–2.454) | 0.001 |
| Chronic kidney disease with hemodialysis | 3.966 (2.731–5.759) | <0.001 | 3.000 (1.931–4.661) | <0.001 |
| Left ventricular ejection fraction <35% | 2.931 (1.866–4.604) | <0.001 | 2.158 (1.345–3.464) | <0.001 |
| Peripheral artery disease | 2.663 (1.897–3.739) | <0.001 | 1.992 (1.384–2.868) | <0.001 |
| History of stroke | 1.645 (1.110–2.473) | 0.013 | 1.221 (0.815–1.831) | 0.333 |
| History of myocardial infarction | 1.307 (0.982–1.739) | 0.067 | ||
| Previous percutaneous coronary intervention | 1.150 (0.869–1.521) | 0.329 | ||
| Previous coronary artery bypass grafting | 1.595 (1.005–2.530) | 0.047 | 0.921 (0.567–1.497) | 0.741 |
| Triple vessel disease | 1.625 (1.146–2.303) | 0.006 | 1.252 (0.873–1.797) | 0.222 |
| Cardiogenic shock status at procedure | 4.032 (1.287–12.625) | 0.017 | 2.984 (0.909–9.792) | 0.071 |
| Left anterior descending coronary artery | 0.742 (0.559–0.985) | 0.039 | 0.777 (0.580–1.041) | 0.091 |
| Left circumflex coronary artery | 1.175 (0.839–1.645) | 0.347 | ||
| Right coronary artery | 1.175 (0.883–1.562) | 0.268 | ||
| Left main coronary artery | 1.221 (0.665–2.242) | 0.519 | ||
| Type B2/C lesion | 1.622 (1.112–2.365) | 0.012 | 1.444 (0.983–2.121) | 0.061 |
| Restenotic lesion | 1.095 (0.715–1.676) | 0.677 | ||
| Chronic total occlusion | 0.742 (0.423–1.301) | 0.297 | ||
| Ostial lesion | 1.139 (0.772–1.678) | 0.510 | ||
| Bifurcation | 0.952 (0.688–1.319) | 0.769 | ||
| Severe calcification on angiography | 1.888 (1.401–2.544) | <0.001 | 1.183 (0.852–1.642) | 0.315 |
| Use of 2.5 mm diameter stent | 0.865 (0.644–1.163) | 0.337 | ||
| Total stent length ≥28 mm | 1.096 (0.812–1.478) | 0.550 | ||
| Use of imaging device for stent placement | 1.064 (0.564–2.009) | 0.848 | ||
| Use of anticoagulant agent | 1.843 (1.309–2.595) | <0.001 | 1.428 (1.003–2.035) | 0.048 |
| Use of statin | 0.636 (0.467–0.866) | 0.004 | 0.946 (0.578–1.549) | 0.826 |
| Use of beta-blocker | 1.038 (0.789–1.365) | 0.791 | ||
| Use of angiotensin-converting enzyme inhibitor | 0.903 (0.685–1.190) | 0.470 | ||
| Use of angiotensin receptor blocker | 1.084 (0.739–1.588) | 0.681 | ||
Note. ACS: acute coronary syndrome; SCAD: stable coronary artery disease; HR: hazard ratio; CI: confidence interval.