Figure 3.
JP downregulates LPS-induced signaling pathway in peritoneal macrophages of MRL/lpr mice. (a) The expression alterations in IRAK1 and NF-κB mRNA. (b) The expression alterations in phosphorylation and nonphosphorylation of IRAK1 and NF-κB protein. (c) The protein expression alterations in TRAF6, IKBα, p-IKBα, and IKKα + IKKβ. (d) The related protein bands. Values are expressed as mean ± SD of three independent experiments. ∗P < 0.05 and ∗∗P < 0.01 versus control cells; #P < 0.05 and ##P < 0.01 versus LPS-treated cells.