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. 2019 Nov 3;2019:2357217. doi: 10.1155/2019/2357217

Figure 4.

Figure 4

JP inhibits the secretion of inflammatory cytokines in peritoneal macrophages of MRL/lpr lupus mice. (a) The expression alterations in TNF-α and IL-6 mRNA. (b) Concentrations of TNF-α and IL-6 in the supernatant of peritoneal macrophages of MRL/lpr mice. (c) Transfection protein bands and transfection efficiency of IRAK1 shRNA in peritoneal macrophages of MRL/lpr mice. (d) After transfection and JP treatment, the alterations of inflammatory cytokine production and TNF-α and IL-6 mRNA in cells. Values are expressed as mean ± SD of three independent experiments. ∗P < 0.05 and ∗∗P < 0.01 versus vehicle control cells; #P < 0.05 and ##P < 0.01 versus LPS or shRNA-treated cells.