Table 2.
Relationships between AKAP6 rs2239647 and glioblastoma risk
| SNP ID | Model | Genotype | Case | Control | Adjusted by age and gender | |
|---|---|---|---|---|---|---|
| OR (95%CI) | p | |||||
| rs2239647 | Allele | C | 817 | 746 | 1.00 | 0.086 |
| A | 329 | 254 | 1.18 (0.98–1.43) | |||
| CC | 302 | 274 | 1.00 | |||
| Genotype | CA | 213 | 198 | 0.98 (0.76–1.26) | 0.849 | |
| AA | 58 | 28 | 1.88 (1.16–3.04) | 0.010 | ||
| Dominant | CC | 302 | 274 | 1.00 | 0.494 | |
| CA-AA | 271 | 226 | 1.09 (0.85–1.38) | |||
| Recessive | CC-CA | 515 | 472 | 1.00 | 0.007 | |
| AA | 58 | 28 | 1.90 (1.19–3.03) | |||
| Additive | AA vs AB vs BB | – | – | 1.18 (0.97–1.42) | 0.091 | |
SNP single nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
p values were calculated by logistic regression analysis with adjustments for age and gender
Bold values indicate statistical significance (p < 0.05)