Table 5.
The association between rs4261436, rs17522122 and astrocytoma patient OS and PFS
| SNP ID | Genotype | OS | PFS | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Log-rank p | SR (1−/3-year) | HR (95%CI) | p | Log-rank p | SR (1−/3-year) | HR (95%CI) | p | ||
| rs4261436 | TT | 0.038 | 0.258/0.033 | 1.00 | 0.176 | 0.152/− | 1.00 | ||
| TC | 0.367/0.116 | 0.70 (0.49–0.99) | 0.045 | 0.178/− | 0.75 (0.53–1.07) | 0.116 | |||
| CC | 0.356/0.111 | 0.81 (0.64–1.02) | 0.078 | 0.267/− | 0.88 (0.70–1.12) | 0.308 | |||
| rs17522122 | GG | 0.025 | 0.268/0.049 | 1.00 | 0.053 | 0.137/− | 1.00 | ||
| GT | 0.352/0.106 | 0.75 (0.59–0.95) | 0.016 | 0.190/− | 0.79 (0.55–1.13) | 0.686 | |||
| TT | 0.341/0.042 | 0.78 (0.54–1.12) | 0.818 | 0.268/− | 0.78 (0.62–0.99) | 0.038 | |||
OS Overall survival, PFS Progression free survival, SR Survival rate, HR Hazard ratio, 95% CI 95% Confidence interval
Log-rank p values were calculated using the Chi-Square test
Bold values indicate statistical significance (p < 0.05)