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Inducers and inhibitors of ferroptosis.
| Ferroptosis inducer | Mechanism of action | Ferroptosis inhibitor | Mechanism of action |
|---|---|---|---|
| Erastin | Suppress system xc- | Ferrostatin-1 | Reduce lipid peroxides |
| Sulfasalazine | Suppress system xc- | Liproxstatin | Reduce lipid peroxides |
| RSL3 | Suppress GPX4 | Deferoxamine | Reduce free iron |
| Sorafenib | Suppress system xc- | Vitamin E | Reduce free iron |
