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miR-200a protected the hearts from DOX-induced chronic cardiotoxicity: (a) schedule of the acute DOX regime experiment; (b) the level of miR-200a in the hearts (n = 6); (c) survival rate in the groups (n = 15); (d) EF in the four groups (n = 10); (e) the level of 4-HNE in the hearts (n = 6); (f) caspase 3 activity (n = 6). ∗P < 0.05 compared with the group with saline. #P < 0.05 compared with mice after DOX injection.
