Table 3.
Greene Climacteric Scale results.
| Group | n | Number (%) of women with symptoms | |||
|---|---|---|---|---|---|
| Before treatment | After treatment | p | |||
| 1. Heart palpitation | Supplement | 114 | 80 (70.1%) | 55 (48.2%) | 0.0008 |
| Placebo | 113 | 76 (67.3%) | 76 (67.3%) | 0.7194 | |
| p | 0.2980 | 0.0215 | |||
| 2. Feeling tense or nervous | Supplement | 114 | 92 (80.7%) | 86 (75.4%) | 0.0003 |
| Placebo | 113 | 90 (79.6%) | 91 (80.5%) | 0.9655 | |
| p | 0.9811 | 0.0012 | |||
| 3. Difficulty sleeping | Supplement | 114 | 98 (85.9%) | 52 (45.6%) | ≤0.001 |
| Placebo | 113 | 82 (72.6%) | 91 (80.5%) | 0.0067 | |
| p | 0.0007 | ≤0.001 | |||
| 4. Increased excitability | Supplement | 114 | 86 (75.4%) | 55 (48.2%) | ≤0.001 |
| Placebo | 113 | 82 (72.6%) | 83 (73.5%) | 0.8861 | |
| p | 0.6274 | ≤0.001 | |||
| 5. Panic attacks | Supplement | 114 | 41 (36.0%) | 27 (23.7%) | 0.0433 |
| Placebo | 113 | 35 (31.0%) | 30 (26.5%) | 0.6298 | |
| p | 0.8248 | 0.2745 | |||
| 6. Difficulty concentrating | Supplement | 114 | 82 (71.9%) | 35 (30.7%) | ≤0.001 |
| Placebo | 113 | 72 (63.7%) | 85 (75.2%) | 0.2535 | |
| p | 0.4192 | ≤0.001 | |||
| 7. Feeling tired or lacking energy | Supplement | 114 | 106 (93.0%) | 54 (47.4%) | ≤0.001 |
| Placebo | 113 | 101 (89.4%) | 105 (93.0%) | 0.0490 | |
| p | 0.0767 | ≤0.001 | |||
| 8. Loss of interest in most things | Supplement | 114 | 69 (60.5%) | 35 (30.7%) | ≤0.001 |
| Placebo | 113 | 52 (46.0%) | 66 (58.4%) | 0.2947 | |
| p | 0.1277 | ≤0.001 | |||
| 9. Sadness or depression | Supplement | 114 | 99 (86.8%) | 40 (35.1%) | ≤0.001 |
| Placebo | 113 | 77 (68.1%) | 88 (78.1%) | 0.0087 | |
| p | 0.0043 | ≤0.001 | |||
| 10. Crying spells | Supplement | 114 | 63 (55.3%) | 44 (38.6%) | 0.0012 |
| Placebo | 113 | 62 (55.0%) | 63 (55.8%) | 0.7053 | |
| p | 0.9988 | 0.0080 | |||
| 11. Irritability | Supplement | 114 | 104 (91.2%) | 50 (44.0%) | ≤0.001 |
| Placebo | 113 | 92 (81.4%) | 98 (86.7%) | 0.0709 | |
| p | 0.1970 | ≤0.001 | |||
| 12. Dizziness or fainting | Supplement | 114 | 54 (47.4%) | 40 (35.1%) | 0.0196 |
| Placebo | 113 | 40 (35.4%) | 35 (31.0%) | 0.7467 | |
| p | 0.3405 | 0.2626 | |||
| 13. Feeling pressure or tightness in the head or other body parts | Supplement | 114 | 73 (64.0%) | 46 (40.4%) | 0.0010 |
| Placebo | 113 | 60 (53.1%) | 57 (50.4%) | 0.9535 | |
| p | 0.4026 | 0.1534 | |||
| 14. Numbness or tingling in some body parts | Supplement | 114 | 65 (57.0%) | 54 (47.9%) | 0.0748 |
| Placebo | 113 | 68 (60.2%) | 65 (57.5%) | 0.8573 | |
| p | 0.4835 | 0.0327 | |||
| 15. Headaches | Supplement | 114 | 99 (86.8%) | 62 (54.4%) | ≤0.001 |
| Placebo | 113 | 93 (82.3%) | 93 (82.3%) | 0.6250 | |
| p | 0.04996 | ≤0.001 | |||
| 16. Muscle and joint pain | Supplement | 114 | 97 (85.1%) | 60 (52.6%) | ≤0.001 |
| Placebo | 113 | 100 (88.5%) | 91 (80.5%) | 0.3175 | |
| p | 0.0574 | ≤0.001 | |||
| 17. Numbness of hands and feet | Supplement | 114 | 49 (43.0%) | 41 (36.0%) | 0.4467 |
| Placebo | 113 | 42 (37.2%) | 40 (35.4%) | 0.8413 | |
| p | 0.5336 | 0.7042 | |||
| 18. Difficulty breathing | Supplement | 114 | 45 (39.5%) | 35 (30.7%) | 0.2542 |
| Placebo | 113 | 36 (32.0%) | 37 (32.7%) | 0.6667 | |
| p | 0.6805 | 0.9836 | |||
| 19. Hot flashes | Supplement | 114 | 101 (88.6%) | 50 (44.0%) | ≤0.001 |
| Placebo | 113 | 86 (76.1%) | 91 (80.5%) | 0.0137 | |
| p | 0.0158 | ≤0.001 | |||
| 20. Night sweats | Supplement | 114 | 92 (80.7%) | 46 (40.4%) | ≤0.001 |
| Placebo | 113 | 85 (75.2%) | 87 (77.0%) | 0.2737 | |
| p | 0.4847 | ≤0.001 | |||
|
| |||||
| 21. Lack of sex drive | Supplement | 114 | 92 (80.7%) | 39 (34.2%) | ≤0.001 |
| Placebo | 113 | 76 (67.3%) | 88 (78.0%) | 0.1692 | |
| p | 0.0089 | ≤0.001 | |||
Number of symptomatic subjects before and after treatment (those that marked that each symptom bothered them at least “a little” as per Greene Climacteric Scale). Bold numbers indicate statistically significant p values.