Table 4.

Genotype and allele frequencies of MSX1, PAX9, and AXIN2 polymorphisms in lateral agenesis.

Polymorphism	Lateral agenesis (N = 47), n	Matched controls (N = 47), n	Statistical analysis for genotypes	Statistical analysis for alleles
MSX1 rs12532 A/G
A/A	21	20	A/G + G/G vs A/A	G vs A
A/G	21	19	Chi-square = 0.04	Chi-square = 0.21
G/G	5	8	p=0.835	p=0.646
A	63	59	OR = 0.91	OR = 0.82
G	31	35
MSX1 rs8670 C/T
C/C	25	33	C/T + T/T vs C/C	T vs C
C/T	19	13	Chi-square = 2.2	Chi-square = 2.57
T/T	3	1	p=0.137	p=0.108
C	69	79	OR = 2.07	OR = 1.9
T	25	15
PAX9 rs61754301 C/T
C/C	47	47	C/T + T/T vs C/C	T vs C
C/T	0	0
T/T	0	0	NA	NA
C	94	94
T	0	0
PAX9 rs4904155 C/G
C/C	18	26	C/G + G/G vs C/C	G vs C
C/G	22	18	Chi-square = 2.09	Chi-square = 2.96
G/G	7	3	p=0.147	p=0.085
C	58	70	OR = 1.99	OR = 1.81
G	36	24
AXIN2 rs2240308 G/A
G/G	9	12	G/A + A/A vs G/G	A vs G
G/A	22	24	Chi-square = 0.24	Chi-square = 1.07
A/A	16	11	p=0.62	p=0.306
G	40	48	OR = 1.44	OR = 1.4
A	54	46

p ≤ 0.001, highly significant; 0.001 ≤ p ≤ 0.05, significant; p ≥ 0.05, not significant.