Table 3.
Baseline demographic and clinical characteristics of cases and controls.
| Characteristic | Cases (adrenocortical tumor) | Controls (normal adrenal) | P value |
|---|---|---|---|
| Patients, n | 400 | 400 | |
| Mean age, years (SD) | 62.7 (12.9) | 58.3 (14.5) | <0.001 |
| Sex | |||
| Female | 268 (67.0%) | 306 (76.5%) | 0.001 |
| Male | 132 (33.0%) | 94 (23.5%) | |
| Race | |||
| White | 294 (73.5%) | 257 (64.3%) | 0.043 |
| Black | 29 (7.25%) | 37 (9.3%) | |
| Hispanic | 16 (4.0%) | 26 (6.5%) | |
| Others | 61 (15.25%) | 80 (20.0%) | |
| Institutional primary care provider | 237 (59.3%) | 251 (62.8%) | 0.31 |
| Mean BMI, kg/m2 (SD) | 29.5 (6.9) | 28.5 (7.0) | 0.047 |
| Interval of abdominal cross-sectional imaging∗, years (SD) | 4.7 (3.8) | 5.9 (4.8) | 0.007 |
| Smoking status | |||
| Nonsmoker | 173 (43.3%) | 216 (54.0%) | 0.37 |
| Current or past smoker | 227 (56.7%) | 184 (46.0%) | |
| Comorbidity | |||
| Hypertension | 242 (60.5%) | 193 (48.2%) | 0.41 |
| Diabetes or prediabetes | 107 (26.7%) | 71 (17.8%) | 0.04 |
| Hyperlipidemia | 207 (51.7%) | 169 (42.2%) | 0.92 |
| Coronary artery disease | 60 (15.0%) | 40 (10.0%) | 0.62 |
| Myocardial infarction | 29 (7.2%) | 16 (4.0%) | 0.50 |
Note. ∗Interval of imaging defined as the time period between the initial and most recent cross-sectional abdominal imaging study.