Table 5.
Risk for benign neoplasia detected via other modalities.
| Other benign neoplasm | Cases (adrenocortical tumor) | Controls (normal adrenal) | OR (95% CI) | AOR (95% CI)∗ |
|---|---|---|---|---|
| n | 400 | 400 | ||
| Meningioma | 11 (2.8%) | 5 (1.3%) | 2.23 (0.80, 7.14) | 2.45 (0.61, 12.42) |
| Pituitary adenoma | 4 (1.0%) | 5 (1.3%) | 0.80 (0.20, 3.03) | 0.64 (0.07, 4.50) |
| Thyroid nodule | 102 (25.5%) | 68 (17.0%) | 1.67 (1.19, 2.36) | 1.77 (1.15, 2.74) |
| Thyroid nodule ≥ 10 mm | 66 (16.5%) | 35 (8.8%) | 1.88 (0.98, 3.63) | 1.72 (0.73, 4.13) |
| FNA benign thyroid | 35 (8.8%) | 17 (4.3%) | 1.62 (0.82, 3.29) | 2.12 (0.87, 5.50) |
| Hyperparathyroidism or parathyroid adenoma | 14 (3.5%) | 5 (1.3%) | 2.87 (1.08, 8.93) | 3.00 (1.00, 11.64) |
| Benign breast Mass | 16 (6.0%) | 10 (3.3%) | 1.62 (0.73, 3.75) | 3.25 (1.28, 8.78) |
| Breast cyst | 24 (9.0%) | 46 (15.0%) | 0.49 (0.29, 0.81) | 0.59 (0.31, 1.10) |
| Colon adenoma | 164 (41.0%) | 136 (34.0%) | 1.34 (1.01, 1.79) | 1.15 (0.80, 1.65) |
| Benign prostatic hyperplasia | 27 (20.5%) | 5 (5.3%) | 5.71 (2.37, 17.00) | 3.20 (1.14, 10.60) |
| Lipoma | 53 (13.3%) | 46 (11.5%) | 1.17 (0.77, 1.79) | 1.08 (0.63, 1.83) |
| Fibroid | 86 (32.1%) | 95 (31.0%) | 0.88 (0.63, 1.22) | 1.36 (0.89, 2.12) |
| Endometrial polyp | 25 (9.3%) | 35 (11.4%) | 0.89 (0.40, 1.79) | 0.78 (040, 1.49) |
| Cervical polyp | 22 (8.2%) | 31 (10.1%) | 0.69 (0.39, 1.21) | 0.92 (0.46, 1.82) |
| Ovarian cyst | 54 (20.1%) | 83 (27.1%) | 0.60 (0.41, 0.86) | 1.40 (0.85, 2.34) |
Note. The unadjusted and adjusted∗ odds ratio for patients with benign adrenocortical tumors (cases) compared with those with normal adrenal glands (controls) are presented along with 95% confidence intervals for each benign neoplasm. AOR: adjusted odds ratio; ∗adjusted for age, sex, race, smoking status, BMI, duration imaging interval, hypertension, hyperlipidemia, composite diabetes (diabetes or prediabetes), coronary artery disease, and myocardial infarction.