Table 1.
Clinical and biochemical characteristics of the study population.
| Variables | TCSS < 6 (n = 86) | TCSS ≥ 6 (n = 100) | p value |
|---|---|---|---|
| Gender (M : F) | 51 : 35 | 67 : 33 | 0.279 |
| Age (y) | 56.221 ± 1.298 | 63.270 ± 1.231 | 0.001∗∗ |
| Duration (y) | 5.836 ± 0.551 | 12.472 ± 0.752 | 0.000∗∗ |
| BMI (kg/m2) | 25.429 ± 3.615 | 25.013 ± 2.854 | 0.391 |
| FPG (mmol/l) | 8.637 ± 0.525 | 9.147 ± 0.496 | 0.362 |
| HbA1c (%) | 8.743 ± 0.289 | 8.778 ± 0.240 | 0.597 |
| C-peptide (ng/ml) | 1.866 ± 0.109 | 1.946 ± 0.136 | 0.839 |
| TG (mmol/l) | 1.563 ± 0.168 | 1.972 ± 0.140 | 0.003∗∗ |
| TC (mmol/l) | 4.437 ± 0.135 | 4.885 ± 0.115 | 0.005∗∗ |
| LDL-C (mmol/l) | 2.550 ± 0.096 | 2.969 ± 0.100 | 0.003∗∗ |
| HDL-C (mmol/l) | 1.103 ± 0.031 | 1.074 ± 0.032 | 0.277 |
| Creatinine (μmol/l) | 63.133 ± 2.223 | 79.520 ± 3.428 | 0.004∗∗ |
| UA (umol/l) | 303.831 ± 10.767 | 349.704 ± 10.631 | 0.003∗∗ |
| BUN (mmol/l) | 5.575 ± 0.212 | 6.488 ± 0.250 | 0.012∗ |
| eGFR (ml/min/1.73 m2) | 115.214 ± 3.325 | 93.660 ± 3.414 | 0.000∗∗ |
| UACR (mg/g) | 219.201 ± 121.144 | 340.638 ± 123.155 | 0.136 |
| CRP (mg/l) | 5.395 ± 0.059 | 5.615 ± 0.095 | 0.008∗∗ |
BMI: body mass index; FPG: fasting plasma glucose; HbA1c: glycated hemoglobin A1c; TG: triglycerides; TC: total cholesterol; LDL-c: low-density lipoprotein cholesterol; HDL-c: high-density lipoprotein cholesterol; UA: uric acid; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; UACR: urinary albumin creatinine ratio; CRP: c-reactive protein. Data are means ± SEM, numbers of patients. ∗p < 0.05, ∗∗p < 0.01. p values for differences between two groups were obtained by two-sample t-test, Mann-Whitney U test, or χ2 test.