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. 2019 Nov 21;7:e8004. doi: 10.7717/peerj.8004

Table 3. Change in Chao 1 diversity, according to socioeconomic status and antibiotic exposure.

Body site/exposure Univariate association Multivariate association1 Multivariate association2
Coefficent p-value Coefficent p-value Coefficent p-value
VAGINAL
Level of EducationA 13.3 0.10 18.2 0.04 17.6 0.05
Prenatal InsuranceB 2.0 0.83 3.4 0.75 3.0 0.78
Marital/CohabitingC 9.8 0.22 8.5 0.31 7.8 0.36
Antibiotics prior to Visit 1 −14.9 0.12 −13.6 0.16 N/A N/A
Antibiotics between Visit 1 and 2 3.0 0.74 3.6 0.69 N/A N/A
ORAL
Level of EducationA −1.4 0.90 −5.2 0.67 −5.0 0.69
Prenatal InsuranceB −16.6 0.19 −23.9 0.09 −23.9 0.10
Marital/CohabitingC 9.8 0.36 7.5 0.51 7.8 0.50
Antibiotics prior to Visit 1 −4.6 0.72 −5.9 0.65 N/A N/A
Antibiotics between Visit 1 and 2 −1.1 0.93 −2.5 0.84 N/A N/A
GUT
Level of EducationA 6.1 0.61 6.5 0.66 7.5 0.62
Prenatal InsuranceB 3.3 0.81 1.2 0.94 1.9 0.91
Marital/CohabitingC −9.4 0.42 −7.1 0.57 −5.9 0.65
Antibiotics prior to Visit 1 6.5 0.62 7.2 0.59 N/A N/A
Antibiotics between Visit 1 and 2 −8.5 0.51 −6.6 0.62 N/A N/A

Notes.

1

Model controlling for age, any previous term birth, any previous preterm birth, weeks between sampling.

2

Model controlling for age, any previous term birth, any previous preterm birth, weeks between sampling, and antibiotics.

A

Education coded as 1 for high school or lower, 0 for some college or higher.

B

Prenatal insurance coded as 1 for Medicaid, 0 for Private.

C

Marital/Co-habiting coded as 1 for Single or Not cohabiting, 0 for Married or Cohabiting.

The bold styling indicates a p-value that is statistically significant at α < 0.05.