Table 4. Bray–Curtis dissimilarity between Visit 1 and Visit 2, according to socioeconomic status and antibiotic exposures for vaginal, oral, and gut body sites.
Body site/exposure | Univariate association | Multivariateassociation1 | Multivariateassociation2 | |||
---|---|---|---|---|---|---|
Coefficent | p-value | Coefficent | p-value | Coefficent | p-value | |
VAGINAL | ||||||
Level of EducationA | 0.046 | 0.41 | 0.022 | 0.72 | 0.015 | 0.81 |
Prenatal InsuranceB | 0.125 | 0.06 | 0.101 | 0.17 | 0.094 | 0.21 |
Marital/Cohabiting | 0.080 | 0.15 | 0.070 | 0.23 | 0.065 | 0.27 |
Antibiotics prior to Visit 1 | 0.054 | 0.41 | 0.050 | 0.74 | N/A | N/A |
Antibiotics between Visit 1 and 2 | 0.056 | 0.37 | 0.051 | 0.41 | N/A | N/A |
ORAL | ||||||
Level of EducationA | 0.068 | 0.01 | 0.077 | 0.015 | 0.060 | 0.05 |
Prenatal InsuranceB | 0.027 | 0.42 | 0.020 | 0.58 | 0.010 | 0.79 |
Marital/CohabitingC | 0.030 | 0.35 | 0.029 | 0.32 | 0.019 | 0.52 |
Antibiotics prior to Visit 1 | 0.012 | 0.73 | 0.008 | 0.82 | N/A | N/A |
Antibiotics between Visit 1 and 2 | 0.083 | 0.006 | 0.083 | 0.008 | N/A | N/A |
GUT | ||||||
Level of EducationA | 0.098 | 0.03 | 0.078 | 0.15 | 0.058 | 0.28 |
Prenatal InsuranceB | 0.079 | 0.12 | 0.038 | 0.51 | 0.020 | 0.73 |
Marital/CohabitingC | 0.140 | 0.001 | 0.130 | 0.004 | 0.11 | 0.02 |
Antibiotics prior to Visit 1 | 0.031 | 0.53 | 0.022 | 0.66 | N/A | N/A |
Antibiotics between Visit 1 and 2 | 0.120 | 0.009 | 0.110 | 0.021 | N/A | N/A |
Notes.
Model controlling for age, any previous term birth, any previous preterm birth, weeks between sampling.
Model controlling for age, any previous term birth, any previous preterm birth, weeks between sampling, and antibiotics.
Education coded as 1 for high school or lower, 0 for some college or higher.
Prenatal insurance coded as 1 for Medicaid, 0 for Private.
Marital/Co-habiting coded as 1 for Single or Not cohabiting, 0 for Married or Cohabiting.
The bold styling indicates a p-value that is statistically significant at α < 0.05.