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MRS reduced the expression of inflammatory mediators regulated by NF-κB signaling after APAP challenge. (a–c) Serum levels of TNF-α, IL-6, and IL-10; (d–f) mRNA expression levels of TNF-α, IL-6, and IL-10; (g, h) western blot results of TNF-α and IL-6 expression; (i, j) western blot analysis showing p65 and p-p65 expression in the liver (∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, and ∗∗∗∗p < 0.0001).
