Table 1. Demographics of enrolled patients.
| No. of subjects (n = 160) | Eosinophilic CRSwNP (n = 40) | Non-eosinophilic CRSwNP (n = 120) | ||||
|---|---|---|---|---|---|---|
| With neutrophilia (n = 7) | Without neutrophilia (n = 33) | P value | With neutrophilia (n = 69) | Without neutrophilia (n = 51) | P value | |
| Sex (female) | 1 | 13 | 0.386 | 10 | 10 | 0.655 |
| Age (yr) | 53 (36–56) | 48 (38–54) | 0.941 | 53 (42–60) | 55 (44–60) | 0.687 |
| Atopic (number) | 4 | 12 | 0.425 | 29 | 25 | 0.719 |
| Asthma (number) | 4 | 3 | 0.012* | 3 | 9 | 0.029* |
| Symptom duration (mon) | 27 (4–60) | 42 (14–180) | 0.244 | 43 (12–120) | 60 (12–120) | 0.600 |
| Lund-Mackay score | 18 (12–23) | 17 (13–19) | 0.727 | 16 (11–20) | 16 (12–20) | 0.554 |
| Global-osteitis score | 20 (8–29) | 15 (6–20) | 0.336 | 13 (8–21) | 13 (4–22) | 0.257 |
| BTT | 3 (0–8) | 0 (0–7) | 0.632 | 3 (0–6) | 3 (0–8) | 0.563 |
| Tissue eosinophil (cells/HPF) | 100.0 (97.2–165.3) | 91.0 (71.0–135.3) | 0.132 | 6.2 (1.0–12.1) | 8.0 (1.9–21.7) | 0.175 |
| Tissue neutrophil (cells/HPF) | 45.0 (43.0–54.5) | 4.5 (1.0–10.3) | < 0.001* | 39.0 (25.0–67.0) | 9.0 (3.3–13.8) | < 0.001* |
| Current smoking (number) | 6 | 5 | < 0.001* | 26 | 17 | 0.707 |
| Smoking history (pack/year) | 7.5 (4.5–43.0) | 0 (0–25.0) | < 0.001* | 0 (0–18.4) | 0 (0–10.0) | 0.207 |
| Alcohol intake (g/mon) | 336 (195–448) | 20 (0–160) | 0.023* | 56 (0–560) | 0 (0–392) | 0.424 |
| BMI (kg/m2) | 25.2 (23.4–29.0) | 23.3 (21.6–24.6) | 0.138 | 24.2 (22.1–26.5) | 24.2 (22.3–26.1) | 0.691 |
Value is presented as median with interquartile range.
CRSwNP, chronic rhinosinusitis with nasal polyps; BTT, butanol threshold test; HPF, high power field; BMI, body mass index.
*Means P value < 0.05.