Table 4. Clinical features of responders and non-responders after 1 year of AIT.
| Characteristics | Responder (n = 34) | Non-responder (n = 14) | P-value | |
|---|---|---|---|---|
| Age (yr) | 42.20 ± 12.51 | 46.00 ± 11.70 | 0.279 | |
| Females | 17 (50.0) | 8 (57.1) | 0.756 | |
| BMI (kg/m2) | 24.45 ± 3.13 | 22.93 ± 4.61 | 0.218 | |
| Age of asthma onset (yr) | 31.36 ± 14.36 | 38.37 ± 10.05 | 0.046 | |
| Age of starting ICS (yr) | 36.90 ± 12.73 | 40.84 ± 10.98 | 0.241 | |
| Age of starting AIT (yr) | 40.09 ± 12.39 | 44.38 ± 11.77 | 0.198 | |
| Time from symptom onset to starting ICS (mon) | 55.99 ± 81.58 | 31.13 ± 43.38 | 0.536 | |
| Time from starting ICS to starting AIT (mon) | 18.01 ± 19.96 | 24.53 ± 32.80 | 0.427 | |
| Time from symptom onset to starting AIT (yr) | 8.73 ± 8.03 | 6.00 ± 4.48 | 0.273 | |
| Allergic rhinitis | 33 (97.1) | 10 (71.4) | 0.059 | |
| Smoking status | - | |||
| Never-smoker | 26 (79.5) | 12 (85.7) | ||
| Ex-smoker | 4 (11.8) | 1 (7.1) | ||
| Current smoker | 4 (11.8) | 1 (7.1) | ||
| Prebronchodilator FEV1 (% predicted) | 87.41 ± 12.88 | 79.12 ± 19.66 | 0.133 | |
| FEV1/FVC (%) | 79.84 ± 7.09 | 80.32 ± 58.01 | 0.940 | |
| Allergen | ||||
| House dust mites | 24 (70.6) | 11 (78.6) | 0.728 | |
| Tree pollens | 12 (35.3) | 4 (28.6) | 0.746 | |
| Weed pollens | 8 (23.5) | 5 (35.7) | 0.480 | |
| Dog dander | 6 (17.6) | 1 (7.1) | 0.656 | |
| Cat dander | 2 (5.9) | 1 (7.1) | > 0.900 | |
| No. of allergens | 2.05 ± 1.22 | 1.66 ± 0.66 | 0.759 | |
| AHR | 19/25 (76.0) | 7/9 (77.8) | > 0.900 | |
Values are presented as means ± standard deviations or number (%).
AIT, allergen immunotherapy; BMI, body mass index; ICS, inhaled corticosteroid; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; AHR, airway hyperresponsiveness.