Figure 4.
THUMPD3-AS1 act as endogenous sponge of miR-543 to regulate ONECUT2 indirectly. (A) THUMPD3-AS1 regulates the protein and mRNA expression of ONECUT2 through miR-543 in A549 and H1299 cells. (B) Luciferase reporter assay was used to confirm the regulating effects of THUMPD3-AS1 on the 3ʹUTR of ONECUT2 through miR-543. (*P < 0.05, error bar refers to SD).