Table 1. List of antiresorptive drugs.
Generic name | Brand name | Manufacture | Dosage (application) | Indication | |
---|---|---|---|---|---|
Bisphosphonate | |||||
Zoledronic acid | Zometa | Novartis pharmaceuticals (Novartis Korea) | 4 mg/100 mL (IV) | Hypercalcemia of malignancy, bone complication due to multiple myeloma and bone metastases from solid tumors | |
Reclat/Aclasta | 5 mg/100 mL (IV) | Osteoporosis, Paget's disease | |||
Alendronate sodium | Fosamax | Merck & Co. (MSD Korea) | 1, 10, 35, 40, 70 mg (PO) | Osteoporosis, Paget's disease | |
Fosamax Plus D | 70 mg (PO) | Osteoporosis | |||
Ibandronate sodium | Boniva/Bonviva | Genentech/Roche (Roche Korea) | 150 mg (PO) | Osteoporosis | |
3 mg (IV) | Osteoporosis | ||||
Bonviva plus | (Alvogen Korea) | 150 mg (PO) | Osteoporosis | ||
Risedronate sodium | Actonel | Warner Chilcott (Handok) | 5, 35, 75, 150 mg (PO) | Osteoporosis, Paget's disease | |
Clodronate disodium | Bonefos | Bayer | 400, 800 mg (PO) | Osteoporosis, hypercalcemia and osteolysis due to malignancy | |
Paget's disease, hypercalcemia due to metastatic bone disease, multiple myeloma | |||||
Tiludronate disodium | Skelid | Sanofi-Aventis | 240 mg (PO) | Paget's disease | |
Pamidronate disodium | Aredia | Novatis Pharmaceuticals (Novartis Korea) | 30, 60, 90 mg (IV) | Hypercalcemia with malignancy, bone metastases, Paget's disease | |
Denosumab | Prolia | Amgen (Amgen Korea) | 60 mg (SC) | Osteoporosis | |
Xgeva | 120 mg (SC) | Skeletal related event with bone metastases |
IV, intravenous injection; PO, per os; SC, subcutaneous injection.