Table 3. Conditions for which major antihypertensive drugs are indicated.
| CCBs | ARBs/ACE inhibitors | Thiazide diuretics | β-blockers | |
|---|---|---|---|---|
| Left ventricular hypertrophy | ● | ● | ||
| Heart failure with reduced ejection fraction (LVEF) | ●* | ● | ●* | |
| Tachycardia | ●‡ | ● | ||
| Angina pectoris | ● | ●† | ||
| Post-myocardial infarction | ● | ● | ||
| Proteinuria/CKD with microalbuminuria | Delete from 2019 | ● | Delete from 2019 |
Changes from 2014 to 2019 are shown in red. Source: generated from Umemura et al.1) and Shimamoto et al.15)
ACE = angiotensin converting enzyme; ARB = angiotensin receptor blocker; CCBs = calcium channel blockers; CKD = chronic kidney disease; LVEF = left ventricular ejection fraction.
*Administration should be started at a low dose, and the dose should be gradually increased carefully; †Caution is needed in patients with coronary spastic angina; ‡Non-dihydropyridine agents.