Table 4. Contraindications and conditions requiring careful drug administration.
| Contraindications | Careful administration | |
|---|---|---|
| CCBs | Bradycardia (Non-dihydropyridines) | Heart failure |
| ARB | Pregnancy | Renal artery stenosis* |
| Hyperkalemia | ||
| ACE inhibitors | Pregnancy | Renal artery stenosis* |
| Angioneurotic edema | Hyperkalemia | |
| Apheresis with a specific type of membrane/hemodialysis | ||
| Thiazide diuretics | Condition in which the body fluid levels of sodium and potassium are markedly decreased | Gout |
| Pregnancy | ||
| Impaired glucose tolerance | ||
| β-blocker | Asthma | Impaired glucose tolerance |
| Severe bradycardia | Obstructive pulmonary disease | |
| Untreated pheochromocytoma | Peripheral arterial disease |
Source: Umemura et al.1)
ACE = angiotensin converting enzyme; ARB = angiotensin receptor blocker; CCB = calcium channel blocker.
*As a rule, ARBs/ACE inhibitors are contraindicated for patients with bilateral renal artery stenosis.