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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Contemp Clin Trials. 2019 Oct 24;87:105854. doi: 10.1016/j.cct.2019.105854

Table 5:

Effects of randomized treatment and non-randomized supplement use on season-adjusted change in serum 25(OH)D concentrations from baseline to 1-year a

Beta (SE) 95% CI p-value
Randomized Vitamin D Treatment 12.74 (0.35) (12.04, 13.43) <.0001
Randomized Omega-3 Treatment −0.56 (0.35) (−1.25, 0.13) 0.115
Non-randomized Supplement use at 1-year
Calcium −0.10 (0.51) (−1.09, 0.90) 0.850
Vitamin D (reference = none)
  ≤400 IU/day 0.61 (0.51) (−0.38, 1.60) 0.230
  401-800 IU/day 2.48 (0.51) (1.48, 3.48) <.0001
  >800 IU/day 6.18 (0.87) (4.48, 7.88) <.0001
Baseline 25(OH)D −0.37 (0.02) (−0.41, −0.33) <.0001
a

multivariable linear regression model of change in total 25(OH)D levels from baseline to 1-year, including Vitamin D treatment, omega-3 treatment and non-randomized Supplement use at 1-year. Based on 1623 observations complete in all covariates.