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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Neurosci Biobehav Rev. 2019 Sep 8;107:215–228. doi: 10.1016/j.neubiorev.2019.09.009

Fig. 3. Activity in the ACC-BLA pathway during observational fear conditioning. Illustrations summarize findings by Allsop et al. (2018).

Fig. 3.

A, Schematic of the observational fear paradigm. Demonstrator mice received tone-shock pairings, while observer mice witnessed these events through a transparent wall from the adjacent compartment. B, Schematic of in vivo neural recordings combined with optogenetic strategies to monitor the activity of either ACC-to-BLA projectors or BLA neurons during the task. C, ACC-to-BLA projectors acquired prominent responses to the shock-predicting cue. D, BLA neurons also acquired prominent responses to the cue, but such responses were abolished by photoinhibition of the ACC input.