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Administration of ferric citrate corrects blood pressure increase in Col4a3KO mice with moderate CKD.
| WT | Col4a3KO | |||
|---|---|---|---|---|
| Ctr | FC | Ctr | FC | |
| Systolic BP (mmHg) | 142±5 | 145±4 | 165±6*$ | 150±4& |
| Diastolic BP (mmHg) | 104±3 | 106±4 | 124±6*$ | 108±5& |
| Mean BP (mmHg) | 117±3 | 119±4 | 137±6*$ | 122±4& |
Non-invasive systolic, diastolic and mean blood pressure (BP) in 10-week old animals. Values are Mean ± SE, n≥11 per group, p<0.05 vs.
WT-Ctr
WT-FC
Col4a3KO-Ctr mice.
