Figure 3.

Comparison of the PT covariate and η approaches for predicted vs. observed prediction‐corrected AUC _0–24. Blue shaded area indicates the 95% confidence interval of the locally estimated scatterplot smoothing regression fit. The gray histograms on top and on the right indicate the frequency distribution of the observed and predicted AUC _0–24. Different symbols indicate different indications (atrial fibrillation = circles, venous thromboembolism prevention = triangles, venous thromboembolism treatment = crosses). AUC _0–24, area under the plasma concentration–time curve from 0 to 24 hours; PT, prothrombin time.