Figure 4.

Mean event-related potentials in 15 subjects homozygous* for ALDH2¹ and 14 heterozygous* subjects after drinking a placebo beverage (solid line) or a beverage containing 0.75 ml/kg alcohol (dotted line). The subjects had to press a button when they heard a rarely presented tone. In both groups, alcohol delayed the appearance of the P300 wave (the segment occurring between 300 and 450 msec) and decreased P300 amplitude, but the effects were stronger in the heterozygous subjects than in the homozygous subjects.

*For further explanation, see figure 2.

SOURCE: Adapted from Wall and Ehlers 1995.