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(a) Photomicrograph of a biopsy specimen from a rectal polyp shows a portion of a tubulovillous adenoma with high-grade dysplasia (Haematoxylin & eosin, × 100). Photomicrographs of an endoscopic submucosal dissection specimen at higher magnification show (b) intramucosal carcinoma with lamina propria invasion only (Haematoxylin & eosin, × 100); and (c) non-dysplastic large bowel mucosa (*) (Haematoxylin & eosin, × 20) at the periphery of a lesion that is completely resected.
