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. 2019 Nov 11;13(4):271–276. doi: 10.22074/ijfs.2020.5684

Table 3.

GHQ-28 and its subscales scores in two study groups in the first and second trimesters of pregnancy


GHQ-28 domain ART pregnancy groupn=40 Spontaneous pregnancy groupn=40 P value 95% CI

The first trimester of pregnancy
Somatic symptoms 8.70 ± 3.00 5.60 ± 3.30 0.001* -4.50, -1.69
Anxiety and insomnia 9.15 ± 3.36 5.80 ± 2.52 0.001* -4.67, -2.02
Social dysfunction 8.55 ± 3.28 6.22 ± 2.61 0.001* -3.64, -1.00
Severe depression 6.85 ± 3.14 5.47 ± 2.83 0.04* -2.70, -0.04
Total general health 33.25 ± 7.41 23.10 ± 5.68 0.001* -13.09, -7.20
The second trimester of pregnancy
Somatic symptoms 9.65 ± 3.18 6.80 ± 3.39 0.001* -4.31, -1.38
Anxiety and insomnia 7.80 ± 2.20 6.35 ± 2.64 0.009* -2.53, -0.36
Social dysfunction 7.52 ± 2.63 6.60 ± 2.76 0.12 -2.12, 0.27
Severe depression 6.05 ± 2.36 6.05 ± 3.39 0.99 -1.30, 1.30
Total general health 31.02 ± 5.54 25.80 ± 6.18 0.001* -7.83, -2.61

Data are presented as mean ± SD. ART; Assisted reproductive technology, CI; Confidence interval, *; Significant difference, GHQ-28; General Health Questionnaire-28, and †; Significant changes compared to the first trimester of pregnancy in the same group.