Table 2.
Association between atopic diseases and iron deficiency anemia
| Atopic diseases | Frequency (%) | Crude OR (95% CI) | P value | Adjusted OR (95% CI) | P value | |
|---|---|---|---|---|---|---|
| No anemia N = (827,124) |
IDA (N = 19,594) |
|||||
| Atopic dermatitis | ||||||
| No | 722,427 (87.34) | 14,853 (75.80) | 1 [Reference] | 1 [Reference] | ||
| Yes | 104,697 (12.66) | 4741 (24.20) | 2.20 (2.13–2.28) | <.001 | 1.42 (1.37–1.47) | <.001 |
| Allergic rhinitis | ||||||
| No | 534,731 (64.65) | 10,344 (52.79) | 1 [Reference] | 1 [Reference] | ||
| Yes | 292,393 (35.35) | 9250 (47.21) | 1.64 (1.59–1.68) | <.001 | 1.25 (1.21–1.29) | <.001 |
| Asthma | ||||||
| No | 600,218 (72.57) | 9393 (47.94) | 1 [Reference] | 1 [Reference] | ||
| Yes | 226,906 (27.43) | 10,201 (52.06) | 2.87 (2.79–2.96) | <.001 | 1.71 (1.65–1.76) | <.001 |
| Atopic diseases, No. | ||||||
| 0 | 388,310 (46.95) | 5170 (26.39) | 1 [Reference] | 1 [Reference] | ||
| 1 | 280,108 (33.87) | 6638 (33.88) | 1.78 (1.72–1.85) | <.001 | 1.30 (1.25–1.35) | <.001 |
| 2 | 132,230 (15.99) | 5804 (29.62) | 3.30 (3.17–3.42) | <.001 | 1.81 (1.73–1.89) | <.001 |
| 3 | 26,476 (3.20) | 1982 (10.12) | 5.62 (5.33–5.93) | <.001 | 2.58 (2.43–2.73) | <.001 |
IDA Iron deficiency anemia
Adjusted by age, sex, insurance type, meningitis, bone and joint infection, sepsis, hepatitis, depression, anxiety, chronic kidney disease, peptic ulcer disease, chronic obstructive pulmonary disease, systemic lupus erythematosus, rheumatoid arthritis, irritable bowel disease, cancer, steroid, methotrexate, cyclosporine