Fig. 1.

Photos and X-rays of teeth and bones in 4 HPP children with HPP. a & b X-rays show general hypomineralization, gracile ribs (arrowhead), small clavicles, shortened long bones and flared metaphysis (arrow) in patient 1 (PA-1) at 2-month-old; c, d & e Premature loss of deciduous tooth (circle) in Patient 2 (PA-2) at 2-year-old; f & g X-rays show flared metaphysis (arrow), and bone destruction (arrowhead) in PA-2; h & i X-ray shows hypomineralization (arrow) in PA-3 at 4-year-old; j Panoramic X-ray in PA-3 at 8-year-old shows decreased mineralization of the alveolar bone, enlarged pulp chambers (arrowhead) and alveolar bone resorption; k & l Bone destruction in the proximal humerus (arrow) of PA-3 at 8-year-old; m & n Premature loss of deciduous tooth (circle) in Patient 4 (PA-4) at 4-year-old; o & p X-ray didn’t show significant bone abnormality